Targeted Therapy Specialist in Aurangabad
Dr. Anup Toshniwal is one of the best Targeted Therapy Specialists in Aurangabad. He has Huge Experience in all types of Targeted Therapy. He is recognized as a Leading oncologist in Aurangabad.
What is Targeted Therapy?
How does targeted therapy work?
There are many types of cells that make up every tissue in your body. For example, there are blood cells, brain cells, and skin cells. Each type has its own job. Cancer starts when certain genes in healthy cells change and become abnormal over time. This change is called a genetic mutation.
Genes tell cells how to make proteins to keep the cell working. If the genes mutate, these proteins change, too. This can make cells divide too much or too quickly and allow the cells to live much longer than they normally would. When this happens, the cells grow out of control and form a tumor. Learn more about the genetics of cancer.
To develop targeted therapies, researchers first identify the genetic changes that help a tumor grow and change. A potential target for this therapy would be a protein that is present in cancer cells but not healthy cells. This can be caused by a mutation. Once researchers have identified a mutation, they develop a treatment that targets that specific mutation.
Targeted therapies can do different things to the cancer cells they target:
Block or turn off signals that tell cancer cells to grow and divide
Prevent the cells from living longer than normal
Destroy cancer cells
To best match the best targeted therapy for your tumor, your doctor may order tests to learn about the genes, proteins, and other factors that are unique to your tumor. This helps find the most effective treatment. Like other treatments, targeted therapies can cause side effects, so it is important that your doctor matches your tumor to the best possible treatment and dose. The dose of targeted therapy that you will receive is based on many factors, like your body weight and your risk of developing severe side effects. Talk to your health care team about why they recommended a certain dose.
Types of Targeted Therapy
Monoclonal antibodies. Drugs called monoclonal antibodies block a spcific target on the outside of cancer cells. The target might also be in the area around this cancer. Monoclonal antibodies can also send toxic substances right to cancer cells. For example, they can help chemotherapy and radiation therapy reach cancer cells better. Monoclonal antibodies are also a type of immunotherapy.
Small-molecule drugs. Drugs called small-molecule drugs can block the process that helps cancer cells multiply and spread. Angiogenesis inhibitors are an example of this type of targeted therapy. Angiogenesis is the process for making new blood vessels. A tumor needs blood vessels to bring it nutrients. The nutrients help it grow and spread. Angiogenesis inhibitors starve the tumor by keeping new blood vessels from forming in the tissue around it.
Other types of targeted therapy include other immunotherapies, angiogenesis inhibitors, and apoptosis inducers (therapies that start cell death, or apoptosis).